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. 2022 Dec 8;9:1048077. doi: 10.3389/fcvm.2022.1048077

TABLE 1.

Baseline clinical data.

Baseline data ARNI ARB Differences between ARNI and ARB
Basic information
Age 67.26 ± 11.97 65.2 ± 9.79 P = 0.434
Male gender 22/35 22/35 P > 0.999
Height (cm) 166.03 ± 8.48 166.89 ± 9.44 P = 0.691
Weight (kg) 70.46 ± 12.34 72.16 ± 13.47 P = 0.584
BMI (kg/m2) 25.47 ± 3.56 25.78 ± 3.38 P = 0.716
Current smoker 16/35 20/35 P = 0.339
Current drinker 15/35 18/35 P = 0.473
Perioperative medications
Statin 18/35 20/35 P = 0.631
SGLT-2i 6/35 4/35 P = 0.495
Spironolactone 9/35 1/35 P = 0.006
Preoperative anti-arrhythmic drugs
β-Blocker 21/35 17/35 P = 0.337
Amiodarone 2/35 3/35 P = 0.643
Postoperative anti-arrhythmic drugs
β-Blocker 1/35 1/35 P > 0.999
Amiodarone 32/35 29/35 P = 0.284
Propafenone 2/35 5/35 P = 0.232
Medical history
Persistent AF 16/35 10/35 P = 0.138
Hypertension 31/35 33/35 P = 0.393
Diabetes mellitus 16/35 19/35 P = 0.473
Hyperlipidemia 24/35 27/35 P = 0.420
CHF 16/35 14/35 P = 0.809
MI 3/35 2/35 P = 0.643
Revascularization 8/35 3/35 P = 0.101
PVD 4/35 2/35 P = 0.393
Stroke/TIA 14/35 11/35 P = 0.454
COPD 5/35 3/35 P = 0.452
CKD 4/35 3/35 P = 0.690
OSAHS 1/35 3/35 P = 0.303
CHA2DS2-VASc 3.54 ± 1.74 3.20 ± 1.53 P = 0.384
Baseline clinical data
HR (beats per minute) 83.14 ± 20.34 80.03 ± 15.75 P = 0.476
SBP (mmHg) 131.49 ± 16.54 133.91 ± 15.66 P = 0.530
DBP (mmHg) 76.74 ± 15.88 73.77 ± 14.10 P = 0.411
Hemoglobin (g/L) 137.54 ± 18.48 139.43 ± 18.81 P = 0.674
Serum creatinine (μmol/L) 88.49 ± 38.97 76.66 ± 16.52 P = 0.103
eGFR (ml/min/1.73 m2) 77.11 ± 23.21 84.31 ± 14.54 P = 0.126
Serum potassium (mmol/L) 3.98 ± 0.30 4.11 ± 0.37 P = 0.108

Baseline characters had no statistical difference between two groups, except for usage of spironolactone.

BMI, body mass index; SGLT-2i, sodium-dependent glucose transporters inhibitor; AF, atrial fibrillation; CHF, congestive heart failure; MI, myocardial infarction; PVD, peripheral vascular; TIA, transient ischemia attack; COPD, chronic obstructive pulmonary disease; CKD, chronic kidney disease; OSAHS, obstructive sleep apnea-hypopnea syndrome; HR, heart rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; RFCA, radiofrequency catheter ablation.