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. 2022 Dec 14;22:19–29. doi: 10.1016/j.reth.2022.11.005

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This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 2 — The characterization of exosomes and the expression of CDKN2B-AS1 in cancer stem cell-like cells (CSCs) and their exosomes.(A) Observation and identification of exosomes under a transmission electron microscope (TEM).(B–C) The expression of CDKN2B-AS1 in CSCs and their parental cells.(D–E) The expression of CDKN2B-AS1 in exosomes derived from CSCs.(F–G) CSCs-derived exosomes were co-cultured with TPC-1 and SW579 cells respectively to observe the localization of PKH67 (green fluorescent label) in the cells. ^ˆˆˆp < 0.001 vs. Control (TPC-1 or SW579 cells); ^&&&p < 0.001 vs. Control-EXO (exosomes derived from TPC-1 or SW579 cells).