Table 1.
Demographic and Clinical Characteristics of 101 Cases of QD-HCCs
| Variable | Male (N = 47) | Female (N = 54) | P valuea |
|---|---|---|---|
| Age, year | |||
| Median (IQR) | 50 (40.0–59.0) | 57 (48.8–64.3) | |
| AFM1 detection, years before HCC diagnosis | |||
| ≤10 | 18 (38.3) | 44 (81.5) | <.001 |
| >10 | 29 (61.7) | 10 (18.5) | |
| HBV infection status, n (%) | |||
| HBsAg (+) | 35 (74.5) | 40 (74.1) | 1.000 |
| HBsAg(-) and anti-HBc(+)b | 12 (25.5) | 14 (25.9) | |
| Serum AFP level, ng/mL, n (%) | |||
| <20 | 21 (44.7) | 20 (37.0) | .564 |
| ≥20 | 26 (55.3) | 34 (63.0) | |
| Cirrhosis, n (%) | |||
| No | 24 (51.1) | 30 (55.6) | .802 |
| Yes | 23 (48.9) | 24 (44.4) | |
| Tumor size, n (%) | |||
| ≤3 cm | 7 (14.9) | 13 (24.1) | .366 |
| >3 cm | 40 (85.1) | 41 (75.9) | |
| Tumor number, n (%) | |||
| 1 | 40 (85.1) | 51 (94.4) | .182 |
| >1 | 7 (14.9) | 3 (5.6) | |
| Edmondson–Steiner grade, n (%) | |||
| I | 0 (0.0) | 2 (3.7) | .247 |
| II–III | 47 (100.0) | 50 (92.6) | |
| Data missing | 0 (0.0) | 2 (3.7) | |
| Vital status,c n (%) | |||
| Alive | 18 (38.3) | 24 (44.4) | .101 |
| Dead | 25 (53.2) | 30 (55.6) | |
| Data missing | 4 (8.5) | 0 (0.0) | |
AFP, α-fetoprotein; anti-HBc, antibodies against the hepatitis B virus core antigen; HBsAg, hepatitis B surface antigen; IQR, interquartile range.
a
Chi-square test or the Fisher exact test.
b
The samples were positive for HBV-DNA test.
c
Followed up for 5 years by May 31, 2019.