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. 2023 Oct 10;5:57. Originally published 2022 Aug 18. [Version 2] doi: 10.12688/hrbopenres.13590.2

Table 1. Eligibility criteria for the systematic review of outcomes used in the dementia with Lewy bodies literature.

Inclusion criteria Exclusion criteria
Publication year •    Any
Language •    No restriction for abstract screening
Types of articles •    Scientific articles published in peer-reviewed journals with available
full texts
•    Popular articles
•    Editorials, commentaries etc.
•    Study protocols
•    Abstracts only
•    Conference abstracts
•    Trial registries
Study design •    Comparative clinical trials (regardless of randomization)
•    Intervention trials with pre-/post assessments regardless of
randomization, case reports
•    Observational studies
•    Reviews, meta analysis (for further
trials)
Population/
Setting
•    People with dementia with Lewy bodies (DLB)
•    18 years and older; all sexes
•    Parkinson’s disease (with and without
mild cognitive impairment; PD-MCI)
•    Atypical parkinsonism (e.g., PPS, MSA)
•    Other dementias (e.g., AD, FTD)
•    Mixed study samples (e.g., Involving
participants with different dementia
subtypes) without separate reporting
for Individuals with DLB
Interventions Any pharmacological, surgical Or non-pharmacological approach for
treating motor and non-motor symptoms in Individuals with DLB at any
disease stage and in any setting (e.g., outpatients as well as inpatients)
Comparators Any:
      •    None
      •    Placebo/Passive control groups/Wait-list
      •    Active control groups (comparison of different pharmacological/
surgical/non-pharmacological interventions)
Outcomes Any:
      •    Standardized quantitative assessments, including neurological
examinations, assessments and tests, and questionnaires (self-and
proxy-rating) across all domains, e.g.;
    ○  Disease severity, motor- and non-motor symptoms
    ○  Patient-Reported Outcome Measures (PROMs) including
quality of life
    ○  Biomarkers, imaging outcomes
    ○  Changes in housing and care situation (e.g., institution)
      •    Carer outcomes included in the patient targeted interventions
will be considered (cf. Rigby 2021: https://pubmed.ncbi.nlm.nih.)
gov/33554912/)
      •    Qualitative approaches to evaluate intervention success across
all domains (e.g., outcomes obtained through patient interviews,
focus groups)
      •    Economic evaluation outcomes (cost analysis, cost-effectiveness
analysis, cost-utility analysis, cost-benefit analysis)