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. 2022 Dec 22;12:22130. doi: 10.1038/s41598-022-25871-2

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Intermediate monocyte subclustering results for (A,B) SF and PBMCs from acute gout and healthy subject groups are shown on UMAP coordinates. Stacked bar plot shows relative abundances. (C) Boxplots of subcluster relative abundance between SF samples and PBMCs of acute gout and healthy subject groups (*P < 0.05). (D) Dot plot of gene expression profiles of the top 10 marker genes in each subcluster.