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. 2022 Dec 22;12:22130. doi: 10.1038/s41598-022-25871-2

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Inflammation score (IS) and energy score (ES) of intermediate monocytes. (A–D) Intermediate monocyte IS and ES values are shown on UMAP coordinates. Boxplots show scores among SF (red) and PBMC samples for acute gout (green) and health (blue) subject groups. (E,F) Boxplots of ISs and ESs among subclusters according to cluster labels. (G,H) ISs and ESs among SF (red) and PBMC samples for acute gout (green) and healthy (blue) subject groups for each subcluster. (*P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001).