Table 1.
Sociodemographic and clinical factors of eligible focus Consortium participants at baseline (n=2401)
| Overall | ColoCare HD | ColoCare FHCRC | ColoCare HCI | COLON | CORSA | EnCoRe | |
| n (%) | 2401 (100) | 298 (12.4) | 150 (6.3) | 80 (3.3) | 1338 (55.7) | 218 (9.1) | 317 (13.2) |
| Age | |||||||
| Mean year±SD | 65.4±10.2 | 63.7±12.2 | 58.3±12.8 | 61.3±11.2 | 66.1±8.7 | 67.3±12.0 | 66.9±9.3 |
| Sex | |||||||
| Female n (%) | 864 (36.0) | 100 (33.6) | 67 (44.7) | 32 (40.0) | 486 (36.3) | 76 (34.9) | 103 (32.5) |
| Male n (%) | 1537 (64.0) | 198 (66.4) | 83 (55.3) | 48 (60.0) | 852 (63.7) | 142 (65.1) | 214 (67.5) |
| Education | |||||||
| Low n (%) | 861 (35.9) | 123 (41.3) | 18 (12.0) | 17 (21.3) | 543 (40.6) | 73 (33.5) | 87 (27.4) |
| Intermediate n (%) | 694 (28.9) | 57 (19.1) | 71 (47.3) | 40 (50.0) | 332 (24.8) | 73 (33.5) | 121 (38.2) |
| High n (%) | 658 (27.4) | 88 (29.5) | 28 (18.7) | 8 (10.0) | 417 (31.7) | 14 (6.4) | 103 (32.5) |
| Unknown n (%) | 188 (7.8) | 30 (10.1) | 33 (22.0) | 15 (18.7) | 46 (3.4) | 58 (26.6) | 6 (1.9) |
| Marital status | |||||||
| Unmarried n (%) | 122 (5.1) | 19 (6.4) | 15 (10.0) | 2 (2.5) | 60 (4.5) | 10 (4.6) | 16 (5.1) |
| Married n (%) | 1738 (72.4) | 193 (64.8) | 71 (47.3) | 50 (62.5) | 1071 (80.0) | 113 (51.8) | 240 (75.7) |
| Divorced/separated n (%) | 138 (5.7) | 24 (8.0) | 11 (7.3) | 10 (12.5) | 64 (4.8) | 14 (6.4) | 15 (4.7) |
| Widowed n (%) | 194 (8.1) | 31 (10.4) | 7 (4.7) | 1 (1.3) | 90 (6.7) | 26 (11.9) | 39 (12.3) |
| Living community n (%) | 20 (0.8) | 0 | 13 (8.7) | 2 (2.5) | 4 (0.3) | 1 (0.5) | 0 |
| Unknown n (%) | 189 (8.9) | 31 (10.4) | 33 (22.0) | 15 (18.7) | 49 (3.7) | 54 (24.8) | 7 (2.2) |
| Smoking status | |||||||
| Current n (%) | 290 (12.1) | 53 (17.8) | 8 (5.3) | 6 (7.5) | 143 (10.7) | 38 (17.4) | 42 (13.3) |
| Former n (%) | 1219 (50.8) | 132 (44.3) | 53 (35.32) | 21 (26.3) | 767 (57.3) | 76 (34.9) | 170 (53.6) |
| Never n (%) | 767 (31.9) | 90 (30.2) | 56 (37.3) | 39 (48.7) | 386 (28.9) | 97 (44.5) | 99 (31.2) |
| Unknown n (%) | 125 (5.2) | 23 (7.7) | 33 (22.0) | 14 (17.5) | 42 (3.1) | 7 (3.2) | 6 (1.9) |
| Alcohol intake | |||||||
| Mean g/day±SD | 13.6±17.1 | 16.1±19.2 | 8.8±18.5 | 2.3±10.2 | 14.0±17.0 | 12.9±16.5 | |
| Unknown n (%) | 633 (26.4) | 208 (69.8) | 81 (54.0) | 60 (75.0) | 54 (4.1) | 218 (100) | 12 (3.8) |
| BMI at diagnosis | |||||||
| Mean kg/m2±SD | 27.1±4.6 | 26.6±4.1 | 28.7±7.3 | 29.4±7.5 | 26.6±4.0 | 27.7±4.4 | 28.3±4.6 |
| Unknown n (%) | 42 (1.7) | 2 (0.7) | 0 | 14 (17.5) | 10 (0.8) | 14 (6.4) | 2 (0.6) |
| Tumour site | |||||||
| Colon n (%) | 1450 (60.4) | 140 (57.0) | 75 (50.0) | 45 (56.3) | 867 (64.8) | 131 (60.1) | 192 (60.6) |
| Rectum n (%) | 862 (35.9) | 143 (48.0) | 60 (40.0) | 22 (27.5) | 434 (32.4) | 78 (35.8) | 125 (39.4) |
| Rectosigmoid n (%) | 42 (1.7) | 15 (5.0) | 15 (10.0) | 7 (8.7) | 0 | 5 (2.3) | 0 |
| Unknown n (%) | 47 (2.0) | 0 | 0 | 6 (7.5) | 37 (2.8) | 4 (1.8) | 0 |
| Tumour stage | |||||||
| I n (%) | 629 (26.2) | 76 (25.5) | 35 (23.3) | 21 (26.3) | 326 (24.4) | 82 (37.6) | 89 (28.1) |
| II n (%) | 694 (28.9) | 114 (38.3) | 49 (32.7) | 23 (28.7) | 386 (28.9) | 52 (23.9) | 70 (22.1) |
| III n (%) | 973 (40.5) | 108 (36.2) | 66 (44.0) | 36 (45.0) | 564 (42.1) | 52 (23.9) | 147 (46.4) |
| Unspecified* n (%) | 16 (0.7) | 0 | 0 | 0 | 4 (0.3) | 12 (5.5) | 0 |
| Unknown n (%) | 89 (3.7) | 0 | 0 | 0 | 58 (4.3) | 20 (9.2) | 11 (3.5) |
| Treatment | |||||||
| Neoadjuvant chemotherapy n (%) | 331 (13.8) | 55 (18.5) | 47 (31.3) | 15 (18.8) | 138 (10.3) | 14 (6.4) | 62 (19.6) |
| Unknown n (%) | 58 (2.4) | 2 (0.7) | 1 (0.7) | 10 (12.5) | 38 (2.8) | 7 (3.2) | 0 |
| Neoadjuvant radiotherapy n (%) | 523 (21.8) | 72 (24.2) | 48 (32.0) | 13 (16.3) | 290 (21.7) | 14 (6.4) | 86 (27.1) |
| Unknown n (%) | 58 (2.4) | 2 (0.7) | 1 (0.7) | 10 (12.5) | 38 (2.8) | 7 (3.2) | 0 |
| Adjuvant chemotherapy n (%) | 682 (28.4) | 100 (33.6) | 80 (53.3) | 32 (40.0) | 315 (23.8) | 56 (25.7) | 99 (31.2) |
| Unknown n (%) | 121 (5.0) | 17 (5.7) | 3 (2.0) | 28 (35.0) | 63 (4.7) | 9 (4.1) | 1 (0.3) |
| Adjuvant radiotherapy n (%) | 227 (9.5) | 188 (63.1) | 7 (4.7) | 1 (1.3) | 16 (1.2) | 13 (6.0) | 2 (0.6) |
| Unknown n (%) | 164 (6.8) | 17 (5.7) | 3 (2.0) | 28 (35.0) | 106 (7.9) | 9 (4.1) | 1 (0.3) |
| Surgery n (%) | 2291 (95.4) | 298 (100.0) | 149 (99.3) | 71 (88.7) | 1290 (96.4) | 195 (89.5) | 288 (90.9) |
| Unknown n (%) | 44 (1.8) | 0 | 0 | 3 (3.8) | 39 (2.9) | 1 (0.5) | 1 (0.3) |
*Distinguishing between stage I and II or II and III not possible.
BMI, body mass index.