Case 1: 50-year-old male with symptoms of chronic productive cough. (A) Chest radiograph showed reticular opacities in the right upper zone of the lung. (B) Chest CT showed intrabronchial aspergilloma in the left upper lobe. Subsequent tests for IgG against Aspergillus were positive and a diagnosis of CPA was made. Diagnosis of CPA hinges on combined clinico-radio-microbiological features.
Case 2: 45-year-old male with past history of tuberculosis presenting with complaints of intermittent hemoptysis. (C) Chest radiograph showed heterogenous opacities in the left upper zone. (D) Chest CT showed air crescent cavity signs in the left upper lobe, suggestive of aspergilloma. Chest radiograph features may be non-specific and advanced chest imaging may be required.
Case 3: 30-year-old male with fever and weight loss over a 4-month period. (E) Chest radiograph showed bilateral reticulonodular opacities in the lung, along with consolidation in the right upper and middle zone. (F) Chest CT showed right and left upper lobe cavities, with pleural thickening. Workup for CPA was positive. Presence of pleural thickening is an important marker of the presence of CPA.