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. 2022 Nov 18;6:7–14. doi: 10.1016/j.ijregi.2022.11.005

Table 2.

Estimates of the incident cases of CPA in India, and associated mortality.

Sub-groups Sub-group population estimate CPA Assumptions for CPA cases and deaths
PTB cases and CPA from (mis)diagnosis and during therapy (steps 1and2)
HIV+, clinically diagnosed 19 320 1 932 10%
HIV−, clinically diagnosed 933800 176 422 19%
HIV+, proven PTB 22 680 1 588 7%
HIV−, proven PTB 1 096200 32 828 3%
Total CPA cases 3 213 828
Deaths from CPA during and immediately after therapy for PTB (step 3)
HIV+ 704 20% CPA mortality over the 12 months after PTB diagnosis
HIV− 42 062 20% CPA mortality over the 12 months after PTB diagnosis
Total CPA deaths in 12 months from PTB diagnosis 42 766
PTB cases and new CPA diagnoses 6–12 months after PTB diagnosis (step 4)
HIV+ 30 380 3 038 10%
HIV− 1 467 350 146 735 10%
Total 149 774
Diagnosed CPA patients in 12 months after PTB diagnosis, including CPA deaths (steps 1,2,3and4)
HIV+ 6 558
HIV− 357 043
Total 363 601
New CPA cases each year, arising 2–5 years after PTB therapy from this annual cohort of PTB cases (step 5)
HIV+, with cavitation 6 016 391 6.5%
HIV+, without cavitation 21 109 43 0.2%
HIV−, with cavitation 18 885 6.5%
HIV−, without cavitation 1 030 082 0.2%
Total 21 379