Table 2.
A summary of the results from the significant linear regression models of predicted C4A expression values on cognitive performance
| Phenotype and Covariates | R | Std. β | Std. Error | Uncorrected p value | FDR |
|---|---|---|---|---|---|
| Pairs matching | |||||
| C4A expression | −0.006 | −0.006 | 0.003 | 1.046 × 10−3 | 9.212 × 10−3 |
| Age | −0.128 | −0.135 | 0.675 | <1 × 10−300 | <1 × 10−300 |
| Sex (Male) | 0.016 | 0.016 | 0.002 | 4.204 × 10−20 | 5.028 × 10−19 |
| Fluid Intelligence | |||||
| C4A expression | −0.009 | −0.008 | 0.016 | 4.174 × 10−3 | 0.032 |
| Age | −0.011 | −0.011 | 0.001 | 2.415 × 10−4 | 2.319 × 10−3 |
| Sex (Male) | 0.066 | 0.059 | 0.012 | 1.209 × 10−101 | 2.838 × 10−100 |
| Symbol Digit Substitution | |||||
| C4A expression | −0.010 | −0.008 | 0.040 | 5.930 × 10−3 | 0.043 |
| Age | −0.451 | −0.455 | 0.002 | <1 × 10−300 | <1 × 10−300 |
| Sex (Male) | −0.007 | −0.006 | 0.029 | 5.477 × 10−2 | 0.248 |
All models also included age squared, educational attainment, genotyping batch, and the first 10 genetic principal components as covariates (data not shown). r = Partial correlation coefficient. Std. β = Standardized β. Std. Error = Standard Error.