Table 1.
Clinical Characteristics of the Enrolled Patients.
| Discovery | Validation | |||||
|---|---|---|---|---|---|---|
| Tot (n = 13) |
CR (n = 9) |
PRPD (n = 4) |
Tot (n = 39) |
CR (n = 29) |
PRPD (n = 10) | |
| Age mean (95% CI) |
71.8 (66.2-75.1) |
73.6 (72.5-75.1) |
67.9 (55.8-80.0) |
70.4 (67.7-73.0) |
69.6 (66.3-72.9) |
72.8 (68.3-77.3) |
| Gender | ||||||
| Female | 2 | 2 | 0 | 7 | 5 | 2 |
| Male | 11 | 7 | 4 | 32 | 24 | 8 |
| Etiology | ||||||
| Alcohol or metabolic | 8 | 5 | 3 | 16 | 11 | 5 |
| Viral | 4 | 4 | 0 | 12 | 9 | 3 |
| Mixed | 1 | 0 | 1 | 11 | 9 | 2 |
| Scores | ||||||
| CTP A/B | 12/1 | 9/0 | 3/1 | 33/6 | 24/5 | 9/1 |
| BCLC 0/A | 3/10 | 2/7 | 1/3 | 6/33 | 4/25 | 2/8 |
| No. of lesions | ||||||
| Single <2cm | 2 | 2 | 0 | 4 | 4 | 0 |
| Single <5cm or 3 nodules ≤3cm |
9 | 6 | 3 | 27 | 20 | 7 |
| Large single or multi | 2 | 1 | 1 | 8 | 5 | 3 |
| AFP (ng/mL) | ||||||
| <20 | 10 | 7 | 3 | 25 | 19 | 6 |
| 20 to 400 | 3 | 2 | 1 | 6 | 3 | 3 |
| >400 | 0 | 0 | 0 | 2 | 2 | 0 |
| Treatment | ||||||
| Resection | 4 | 1 | 3 | 14 | 9 | 5 |
| RF | 9 | 8 | 1 | 25 | 20 | 5 |
Abbreviations: AFP: alpha-fetoprotein; BCLC: Barcelona Clinic Liver Cancer; CR: complete responder; CTP: Child–Turcotte-Pugh; PRPD: partial responder and progressive disease; RF: radiofrequency ablation.