TABLE 2.

Absolute values of the lesion volume (mm³) determined by T₂-weighted magnetic resonance imaging of the mouse brain 1 day (D1) and 7 days (D7) after pMCAO.

	D1	D7	% of decrease	N
Ctrl	24.85 ± 7.29	3.32 ± 1.50	87.52 ± 2.31	6
Aqp4–/–	41.51 ± 3.90	12.35 ± 2.30	70.61 ± 4.57	5
Trpv4–/–	47.37 ± 2.70	14.08 ± 2.42	71.11 ± 13.47	5
Aqp4–/–/ Trpv4–/–	4.15 ± 1.29	1.64 ± 0.56	54.05 ± 14.79	5

Ctrl, control; Aqp4^–/–, AQP4-deficient mice; Trpv4^–/–, TRPV4-deficient mice; Aqp4^–/–/Trpv4^–/–, AQP4- and TRPV4-deficient mice; N represents the number of animals in the group.