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Contrasting trees. a) Caterpillar tree with 
, 
, 
, 
, 
, 
. b) Fully symmetric bifurcating tree with 
, 
, 
, 
, 
. c) Star tree with 
, 
, 
and 
undefined, 
. d) Clone tree of the lung tumor CRUK0065 in the TRACERx cohort (Jamal-Hanjani et al. 2017). In the clone tree, nodes represented by empty circles correspond to extinct clones, and the diameters of other nodes are proportional to the corresponding clone population sizes.
