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. 2022 Jul 19;162(6):1241–1254. doi: 10.1016/j.chest.2022.07.008

Table 3.

Multinomial Logit Model 1 Results

Attribute Parameter (Level) Marginal Effect (95% CI)
Opt-out constant 0.4 (–0.35 to 1.16)
Lung function Modest deterioration (–5%) –0.45a (–0.79 to –0.11)
No change Referent
Modest improvement (+5%) 0.65b (0.36 to 0.95)
Excellent improvement (+15%) 1.24b (0.77 to 1.72)
Need for IV antibiotics No change Referent
One-half the number of IV courses 0.27a (0.1 to 0.44)
Abdominal symptoms No change Referent
Improvement in symptoms 0.26a (0.02 to 0.51)
Improvement in symptoms and a reduction in pancreatic enzymes 0.37b (0.17 to 0.58)
Life expectancy No change Referent
Increases by 5 y 0.55b (0.27 to 0.82)
Increases by 10 y 1.85b (1.45 to 2.26)
Increases by 15 y 2.34b (1.83 to 2.85)
Overall quality of life No change Referent
Good improvement (+10%) 0.31a (0.12 to 0.5)
Excellent improvement (+20%) 0.65b (0.43 to 0.88)
Use of inhaled medicines No change Referent
A modest reduction in time spent (–25%) 0.18a (0.01 to 0.35)
A large reduction in time spent (–50%) 0.3a (0.11 to 0.48)
Physiotherapy/ACT No change Referent
Time spent on physiotherapy is halved 0.19a (0.07 to 0.32)
Able to fully stop physiotherapy 0.51b (0.26 to 0.75)
Model statistics No. of observations, 1,236; McFadden R2, 0.32; LL, –924; AIC, 1,882; BIC, 1,988

ACT = airway clearance therapy; AIC = Akaike information criteria; BIC = Bayesian information criterion; LL = log likelihood.

a

P < .05.

b

P < .001.