Table 5. Evaluation of Synthesized Compounds Using In Silico ADME.

compounds	MW	no. of H-bond acceptors	no. of H-bond donors	WLOGP	GI absorption	BBB permeant	Lipinski no. of violations	PAINS no. of alerts
9	336.36	6	2	2.49	high	no	0	0
10	304.36	4	2	3.09	high	no	0	0
11	417.89	7	3	3.47	low	no	0	0
12	342.17	4	2	3.78	high	yes	0	0
13	269.3	3	2	3.06	high	yes	0	0
14	304.73	3	1	3.93	high	yes	0	0
15	372.18	4	1	6.3	high	no	1	0
17	508.98	9	4	2.75	low	no	2	0
18	360.38	5	3	2.34	high	no	0	0
19	474.71	5	2	4.49	low	no	0	0
20	332.37	4	3	2.35	high	no	0	0
21	358.41	4	2	2.84	high	no	0	0
22	395.82	5	2	3.2	low	no	0	0
23	463.27	6	2	5.57	high	no	0	0
24	300.38	2	3	2.95	high	no	0	0
25	328.39	3	3	2.94	high	no	0	0
26	369.27	2	3	4.25	high	no	0	0