TABLE 2.
Donor inclusion/exclusion criteria.
| Inclusion criteria |
| Age: 18–50 ani (Children under 18 can only donate with parental consent) BMI 18.5–30 kg/m2 Should feel good at the time of donation and are similar to age as recipient, if possible |
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| Exclusion criteria |
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| High risk behavior |
| ○ Use of drugs or other injections without a prescription |
| ○ Exposure to HIV, HBV, or HCV in the last 12 months |
| ○ Unprotected sexual contact or prostitution in the last 12 months |
| ○ Tattoos and piercings made in the last 6 months |
| ○ Incarceration |
| ○ Risk factors for Creutzfeldt-Jakob disease |
| ○ Chronically poor diet ○ Homelessness |
| ○ Pregnancy |
| ○ Frequent activities involving animal (to exclude the risk of transmission of zoonotic infections) |
| ○ Diarrhea (more than three stools per day) among close contacts members (including children) within 4 weeks before donation |
| ○ Person is in a vulnerable group, unable to take care of him/her or unable to protect him/her from significant harm or exploitation |
| Current contagious diseases |
| ○ Fever, vomiting, diarrhea, or other symptoms of infection in the last 4 weeks |
| ○ Vaccinations or injections in the last 8 weeks |
| ○ Blood transfusion, accidental sting with needles exposed to another person’s blood or biological fluids in the last 12 months |
| ○ International travel to countries with poor hygiene, in the last 6 months |
| Other conditions |
| ○ Family members with active gastrointestinal infections |
| ○ Antibiotic treatment in the last 3 months |
| ○ Organ/tissue transplantation ○ Helicobacter pylori induced ulcers |
| ○ Gastrointestinal diseases, celiac disease, irritable bowel syndrome, chronic constipation, gastrointestinal tumors, or major gastrointestinal tract surgery |
| ○ Family history of colorectal cancer (more than 2 grade two relatives have/have had the disease) |
| ○ Autoimmune disease |
| ○ Treatment with immunomodulatory drugs ○ Other cancers and active chemotherapy for other diseases ○ History of metabolic syndrome, obesity (BMI > 30 kg/m2) or malabsorption ○ Chronic pain syndrome or other neurodegenerative diseases ○ Diabetes ○ Autism ○ Cardiovascular disease, stroke ○ Active or history of mental illness; depression requiring treatment |
| ○ Systemic autoimmunity or atopic diseases |
| ○ Anterior prosthetic implant (e.g., metal heart valve, joint replacement, ventricular-peritoneal shunt, cardiac stent) |
| ○ Allergy to tested antibiotics |
| ○ Known contagious disease or at least 2 weeks after complete recovery from infectious diseases (e.g., chickenpox) |