Fig. 4.

Functional analysis of NEK5 interactors identified by BioID. A Cell signaling pathway enrichment of NEK5 biotinylated proteins. Data were analysed using Metascape [24]. B Major protein interaction networks in the NEK5 interactome. Analysis was undertaken using STRING/Cytoscape. The node size indicates the fold change (FC) for biotinylation in NEK5-BioID-MYC-expressing cells versus control and the node border width indicates the p value. Proteins with higher FC and lower p value are represented by larger nodes with wider border