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. 2022 Dec 22;21(1):94–100. doi: 10.1016/j.jtha.2022.10.013

Figure 2.

Figure 2

Thrombi geometry in post-COVID syndrome (PCS). (A) Thrombi geometry is represented as thrombi area (i), length (ii), width (iii), and the number of thrombi (iv) on collagen-coated channels in controls (black, n = 42) vs patients with PCS (red, n = 21). Data displayed as mean±SD and analyzed using unpaired Student’s t-test. ∗∗p < .01, ∗∗∗p < .001, ∗∗∗∗p < .0001. (B) Graphical representation of thrombi forming on collagen in patients with PCS (red) vs controls (gray). The mean length and width of thrombi are shown for individual patients/controls, with the mean thrombi geometry for all patients. The 95% confidence interval (CI) for controls is shown in the gray area. (C) Correlation analysis between thrombi length on collagen-coated channels and von Willebrand factor (VWF)(Ag):ADAMTS13 (i) or the area under the curve (AUC) in thrombin generation assay (ii). Data analyzed using Pearson correlation coefficients. (D) Difference in thrombi length in controls vs patients with normal/raised AUC (i), VWF(Ag) (ii), or VWF:ADAMTS13 (iii). Data analyzed using 1-way anova test. ∗p < .05, ∗∗∗∗p < .0001.