Table 2.

IC₅₀ values for cytotoxic drug diffusion coefficients D_γ and cell maturation ages A^mat, for both monolayer and spheroid in silico cultures

Dγ μm2/s	Amat = 18 h	Amat = 30 h	Amat = 50 h
Summary of IC50 values in the monolayer model
1	4.2675	3.2892	2.7924
10−2	4.2706	3.2876	2.7966
10−4	4.2913	3.2962	2.8088
Summary of IC50 values in the cross section spheroid model
1	3.9644	3.2315	2.9875
10−2	5.0965	5.2505	4.9565
10−4	5.1837	6.6280	9.5846