Table 3.

IC₅₀ values for anti-mitotic drug diffusion coefficients D_γ and cell maturation ages A^mat, for both monolayer and spheroid in silico cultures

Dγ μm2/s	Amat = 18 h	Amat = 30 h	Amat = 50 h
Summary of IC50 values in the 2D model
1	4.2988	3.3495	3.2190
10−2	4.3018	3.3641	3.1989
10−4	4.3037	3.3656	3.2361
Summary of IC50 values in the 3D model
1	3.8735	3.3896	3.4942
10−2	5.3333	5.7667	7.4052
10−4	4.8457	9.0081	18.148