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. 2022 Dec 6;7(50):46955–46971. doi: 10.1021/acsomega.2c06057

Table 4. IC50 Values of TJ08 against Various Cancer Cells and Normal Cellsa.

  IC50 (μM)
compd Jurkat K562 MOLT-4 HeLa HCT116 MIA-PaCa-2 HEK
TJ08 1.88 ± 0.51 1.89 ± 0.55 2.05 ± 0.72 2.11 ± 0.62 3.04 ± 0.8 3.82 ± 0.25 >50
DOXO 4.89 ± 0.11 0.99 ± 0.21 >1 0.21 ± 0.13 0.26 ± 0.19 0.059 ± 0.63 >50
a

MTT assay, cell treated with TJ08 and incubated for 48 h. IC50 (μM) (mean ± SD, n = 3).