Table 2. Antitubercular Activity in MIC in μM (μg/mL) and 9a–i.
Compd | R | M. tuberculosis H37Rv μM (μg/mL) |
---|---|---|
9a | C6H5 | 57.73 (25) |
9b | 4-BrC6H4 | 12.23 (6.25) |
9c | 4-ClC6H4 | 6.68 (3.12) |
9d | 4-CH3C6H4 | 6.98 (3.12) |
9e | 2-CNC6H4 | 27.29 (12.5) |
9f | 3-CNC6H4 | 6.81 (3.12) |
9g | 4-CNC6H4 | 3.49 (1.6) |
9h | 3,5-F2C6H3 | 3.41 (1.6) |
9i | 6-F-pyridin-3-yl | 3.53 (1.6) |
pyrazinamide | 25.36 (3.12) | |
isoniazid | 11.67 (1.6) | |
rifampicin | 0.97 (0.8) |