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. 2022 Dec 8;12:1080475. doi: 10.3389/fonc.2022.1080475

Table 3.

Comparison of surgical outcomes between LNY ≥ 12 group and < 12 group.

Variables All (n=257) Before matching After matching
LNY ≥ 12 LNY < 12 P value LNY ≥ 12 LNY < 12 P value
(n=98) (n=159) (n=87) (n=87)
Period of operation       0.356     0.165
 2010-2015 101 (39.3) 35 (35.7) 66 (41.5)   31 (35.6) 40 (46.0)  
 2016-2018 156 (60.7) 63 (64.3) 93 (58.5)   56 (64.4) 47 (54.0)  
Type of surgery       0.421     0.459
 LAR 126 (49.0) 48 (49.0) 78 (49.1)   42 (48.3) 36 (41.4)  
 ELAPE 108 (42.0) 41 (41.8) 67 (42.1)   38 (43.7) 46 (52.9)  
 APR 19 (7.4) 8 (8.2) 11 (6.9)   7 (8.0) 5 (5.7)  
 Hartmann’s procedure 4 (1.6) 1 (1.0) 3 (1.9)   0 0  
Surgeons       0.715     0.517
 Senior 223 (86.8) 86 (87.8) 137 (86.2)   76 (87.4) 73 (83.9)  
 Junior 34 (13.2) 12 (12.2) 22 (13.8)   11 (12.6) 14 (16.1)  
Operative time, median (IQR),min 216 (180-260) 219 (185-261) 215 (180-260) 0.952 215 (180-255) 216 (180-258) 0.680
Blood loss, median (IQR),ml 50 (30-100) 50 (20-100) 50 (30-100) 0.167 50 (20-100) 50 (30-100) 0.092
Conversion to open surgery, n (%) 8 (3.1) 4 (4.1) 4 (2.5) 0.485 3 (3.4) 3 (3.4) 1.000
30-d complications, n (%) 29 (11.3) 9 (9.2) 20 (12.6) 0.403 9 (10.3) 12 (13.8) 0.485
Clavien-Dindo classification, n (%)       0.693     0.744
 I-II 23 (8.9) 7 (7.1) 16 (10.1)   7 (8.0) 10 (11.5)  
 III-IV 6 (2.3) 2 (2.0) 4 (2.5)   2 (2.3) 2 (2.3)  
Reoperation, n (%) 5 (1.9) 1 (1.0) 4 (2.5) 0.652 1 (1.1) 2 (2.3) 1.000
30-d Mortality, n (%) 1 (0.4) 1 (1.0) 0 0.381 1 (1.1) 0 1.000
Postoperative LOS, median (IQR), d 7 (6-9) 7 (6-9) 7 (6-9) 0.502 7 (6-9) 8 (7-9) 0.180
Follow-up, median (IQR),m 65 (54-75) 67 (52-75) 64 (55-74) 0.778 67 (52-75) 67 (54-72) 0.929
Recurrence*, n (%) 60 (23.3) 23 (23.5) 37 (23.3) 0.971 20 (23.0) 23 (26.4) 0.598
Locoregional recurrence, n (%) 10 (3.9) 5 (5.1) 5 (3.1) 0.512 4 (4.6) 5 (5.7) 1.000
Distant metastasis, n (%) 54 (21.0) 20 (20.4) 34 (21.4) 0.852 17 (19.5) 18 (20.7) 0.85

LNY, lymph node yield; LAR, low anterior resection; ELAPE, extralevator abdominoperineal excision; APR, abdominoperineal resection; LOS, length of stay.

*Four patients had both locoregional recurrence and distant metastasis.