Table 2. Risk score and chemotherapy drugs sensitivity in ccRCC patients.

Drug	Correlation Coefficient	P-value for correlation	IC50 value (median ± SD)		P-value for sensitivity
			Low risk group	High risk group
GSK429286A	−0.4116847	9.03E−23	5.202 ± 0.593	4.873 ± 0.81	2.75E−15
Pyrimethamine	−0.4008079	1.22E−21	4.282 ± 0.925	3.537 ± 1.098	5.02E−15
Tubastatin A	−0.3752999	7.17E−19	4.841 ± 0.655	4.487 ± 0.983	1.27E−12
GNF-2	−0.3697642	1.74E−18	2.509 ± 0.212	2.381 ± 0.277	2.36E−11
OSU-03012	−0.3339629	3.60E−15	2.148 ± 0.87	1.739 ± 0.957	1.02E−09
AUY922	−0.3162495	1.11E−13	−3.092 ± 0.575	−3.337 ± 0.566	3.26E−10
BI-2536	−0.3140472	1.67E−13	−2.082 ± 0.534	−2.324 ± 0.618	6.02E−08
YM155	−0.299257	2.41E−12	−1.343 ± 6.914	−3.863 ± 6.499	4.06E−07
MS-275	−0.2928415	8.04E−12	1.669 ± 1.596	0.922 ± 1.778	9.92E−08
FTI-277	−0.2830392	3.80E−11	2.161 ± 0.229	2.048 ± 0.286	2.43E−09
CGP-60474	−0.2801646	6.08E−11	−2.236 ± 0.752	−2.437 ± 0.688	1.05E−07
WZ3105	−0.2796805	9.98E−11	1.393 ± 1.891	0.666 ± 2.211	2.43E−06
Vinorelbine	−0.2763082	1.13E−10	−3.305 ± 1.291	−3.819 ± 1.425	1.45E−06
LAQ824	−0.272809	1.98E−10	−2.507 ± 0.854	−2.854 ± 0.942	3.77E−07
BMS-754807	−0.2660241	5.69E−10	0.838 ± 0.636	0.546 ± 0.762	1.88E−07
Phenformin	−0.2656272	6.05E−10	7.963 ± 0.91	7.547 ± 1.068	2.32E−06
GW-2580	−0.2635171	1.25E−09	5.759 ± 0.924	5.502 ± 1.334	2.09E−06
NSC-207895	−0.2633884	8.52E−10	4.27 ± 0.915	3.947 ± 0.989	1.34E−05
Zibotentan	−0.2611228	1.20E−09	5.567 ± 0.209	5.478 ± 0.219	5.62E−07
Salubrinal	−0.2593582	2.01E−09	4.363 ± 1.25	3.719 ± 1.492	7.17E−06
CP466722	−0.2555132	2.76E−09	3.095 ± 1.137	2.625 ± 1.333	3.18E−06
NG-25	−0.2477181	8.52E−09	3.007 ± 0.845	2.73 ± 1.088	1.07E−05
JNK-9L	−0.2440906	1.42E−08	−0.144 ± 0.531	−0.34 ± 0.6	1.10E−05
JW-7-24-1	−0.2338737	5.75E−08	1.775 ± 0.72	1.479 ± 0.903	6.94E−06
PHA-665752	−0.2262784	1.56E−07	2.864 ± 0.212	2.798 ± 0.271	6.67E−06
JQ12	−0.2214814	2.88E−07	1.688 ± 1.216	1.353 ± 1.331	2.88E−05
A-443654	−0.2167294	5.21E−07	−0.803 ± 0.312	−0.871 ± 0.366	0.00069563
Etoposide	−0.2154125	6.12E−07	1.737 ± 0.967	1.368 ± 1.227	3.73E−05
Lisitinib	−0.2140062	7.45E−07	2.292 ± 0.59	2.001 ± 0.836	1.15E−06
Mitomycin C	−0.198886	4.30E−06	−0.598 ± 0.849	−0.928 ± 0.934	9.40E−06
5-Fluorouracil	−0.1917897	9.45E−06	3.674 ± 1.028	3.368 ± 1.114	6.08E−06
KIN001-135	−0.1808101	3.03E−05	3.889 ± 0.253	3.793 ± 0.325	0.00061634
Doxorubicin	−0.1787203	3.75E−05	−1.719 ± 0.627	−1.916 ± 0.81	0.00113553
AZ628	−0.1781504	0.00029364	5.71 ± 2.579	4.896 ± 2.837	0.00297656
TAK-715	−0.1702494	0.00010176	4.657 ± 1.055	4.349 ± 1.277	0.00130195
Crizotinib	−0.1637402	0.00030632	3.094 ± 0.88	2.851 ± 1.197	0.01034253
LY317615	−0.160018	0.0002287	3.346 ± 0.612	3.082 ± 0.679	1.57E−05
AS605240	−0.1598432	0.00028584	3.831 ± 1.434	3.449 ± 1.679	0.00634062
Sorafenib	−0.1433182	0.00118607	2.799 ± 1.447	2.534 ± 1.68	0.02333714
CP724714	−0.1393836	0.00150345	4.617 ± 0.785	4.516 ± 0.91	0.01613482
TL-1-85	−0.1369686	0.00170886	3.66 ± 1.051	3.47 ± 1.234	0.00884412
VX-680	−0.1223163	0.00496696	1.107 ± 0.813	0.936 ± 0.998	0.01145153
GW843682X	−0.1101968	0.01143801	−2.886 ± 1.025	−2.965 ± 1.119	0.02462889
GSK1904529A	0.10348973	0.01758529	2.261 ± 0.283	2.287 ± 0.289	0.02385087
CGP-082996	0.12168176	0.00532862	1.451 ± 3.49	1.893 ± 3.837	0.04197339
Dasatinib	0.136895	0.0018856	−0.708 ± 3.034	0.201 ± 3.198	0.01358105
Z-LLNle-CHO	0.13805049	0.00150446	0.263 ± 1.627	0.403 ± 1.507	0.01753678
Rapamycin	0.15665587	0.00031024	−2.749 ± 1.604	−2.523 ± 1.713	0.00827571
Lapatinib	0.15866254	0.0002588	2.268 ± 0.832	2.431 ± 0.835	0.00580935
Shikonin	0.16179519	0.00019418	−0.997 ± 3.32	−0.591 ± 3.634	0.00529048
XMD8-85	0.16653263	0.00014891	0.466 ± 8.166	1.222 ± 8.87	0.00678214
Ruxolitinib	0.17062802	8.53E−05	3.906 ± 0.472	4.039 ± 0.556	0.0114337
Midostaurin	0.17622863	4.82E−05	−0.858 ± 2.128	−0.446 ± 2.277	0.00351609
BX-912	0.177726	4.15E−05	2.573 ± 1.062	2.858 ± 1.306	0.00592782
Obatoclax Mesylate	0.18180522	2.73E−05	−1.836 ± 2.237	−1.316 ± 2.363	0.00139064
GSK-650394	0.18184426	2.72E−05	3.063 ± 0.854	3.357 ± 1.044	0.00263797
KIN001-102	0.18465183	2.03E−05	2.466 ± 0.682	2.636 ± 0.839	0.00197243
Bryostatin 1	0.18612326	2.38E−05	−3.542 ± 1.523	−3.184 ± 1.709	0.00529447
XL-184	0.18723462	1.54E−05	2.219 ± 1.298	2.493 ± 1.425	0.00124207
WZ-1-84	0.1894432	1.27E−05	3.504 ± 1.102	3.763 ± 1.103	0.00109396
QS11	0.19118071	1.01E−05	2.886 ± 0.968	3.157 ± 1.181	0.00151151
Bleomycin	0.19127995	1.02E−05	0.006 ± 3.981	0.776 ± 4.472	0.00150329
AS601245	0.1931847	8.11E−06	1.962 ± 0.409	2.066 ± 0.438	0.00075864
CMK	0.19339315	7.93E−06	1.154 ± 2.384	1.664 ± 2.546	0.00048235
Parthenolide	0.19787401	5.13E−06	2.076 ± 1.924	2.608 ± 2.121	0.00108445
Saracatinib	0.20334878	9.68E−06	1.193 ± 2.263	2.109 ± 2.329	0.00163244
NSC-87877	0.2054239	3.32E−06	4.11 ± 1.689	4.579 ± 1.875	0.00287139
FR-180204	0.2073988	1.61E−06	4.913 ± 0.32	4.971 ± 0.349	0.00070296
Pazopanib	0.20879199	1.36E−06	2.636 ± 1.269	2.982 ± 1.427	0.00019755
FMK	0.21931092	3.78E−07	4.629 ± 0.954	4.927 ± 1.068	0.00014473
XMD14-99	0.22055458	7.39E−07	3.562 ± 1.773	4.14 ± 1.951	0.00092496
CAL-101	0.2394262	3.25E−08	3.432 ± 1.979	4.083 ± 2.134	5.39E−05
Thapsigargin	0.24828123	7.87E−09	−5.281 ± 3.865	−4.504 ± 4.747	4.48E−06
ZSTK474	0.25063554	5.61E−09	0.436 ± 1.358	0.964 ± 1.538	1.49E−05
AKT inhibitor VIII	0.2598575	1.45E−09	2.277 ± 0.286	2.367 ± 0.286	1.41E−07
DMOG	0.27301586	1.91E−10	5.339 ± 1.995	6.165 ± 2.518	5.66E−07