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. 2022 Nov 24;11(4):74. doi: 10.3390/antib11040074

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Evaluation of EpMab-37-mG_2a-f mediated ADCC and CDC activities in BT-474 and Capan-2 cells. (A,C) ADCC elicited by EpMab-37-mG_2a-f or control mouse IgG_2a against BT-474 (A) and Capan-2 (C) cells. (B,D) CDC elicited by EpMab-37-mG_2a-f or control mouse IgG_2a against BT-474 (B) and Capan-2 (D) cells. Values are shown as mean ± SEM. Asterisks indicate statistical significance (** p < 0.01, * p < 0.05; Welch’s t-test). ADCC, antibody-dependent cellular cytotoxicity; CDC, complement-dependent cytotoxicity.