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. 2022 Dec 12;9(12):792. doi: 10.3390/bioengineering9120792

Figure 2.

Figure 2

The AMG510 sensitivity of 2D NCl-H23 and CT-26 cells under normoxia and hypoxia conditions. (a) Cell viability of the NCl-H23 cell line treated with AMG510 for 48 h in 2D; the drug doses include 0.001 μM, 0.005 μM, 0.01 μM, and 1 μM. (b) The bright field images of NCl-H23 treated with AMG510 in 2D. (I) Normoxia. (II) Hypoxia. (c) Cell viability of the CT-26 cell line treated with AMG510 for 48 h in 2D; the drug doses include 0.001 μM, 0.005 μM, 0.01 μM, and 1 μM. (d) The bright field images of CT-26 treated with AMG510 in 2D; scale bar: 200 μM. (I) Normoxia. (II) Hypoxia. ns: not significant.