Figure 3. Comparison of Read2Tree with regular pipeline with assembly, orthology prediction and multiple sequence alignment computation.

(A) Comparison of trees using the difference between the reference tree between either the tree of Read2Tree and the tree coming from the assembly approach. For dark blue we had only Read2Tree trees as assemblies for these low coverages are not possible to obtain. Below zero (in dark or light blue), Read2Tree is more accurate, while above zero (in red), the assembly approach is more accurate. In grey, no difference between the methodologies. (B) Comparison of wall time needed from reads to availability of concatenated multiple sequence alignment showing the dependencies of available closest remaining reference and coverage.