Table 1.
Effect of βCAR on oxidative stress biomarkers in cerebral I/R rats.
| GSH (μmol/g) |
SOD (U/g) |
MDA (nmol/g) |
GPx (U/g) |
CAT (U/g) |
|
|---|---|---|---|---|---|
| Sham | 3.3 ± 0.11 b | 87.4 ± 0.3 b | 14.0 ± 0.89 b | 302.0 ± 19.73 b | 2.79 ± 0.061 b |
| I/R control | 1.7 ± 0.07 a | 52.5 ± 2.9 a | 30.6 ± 2.12 a | 150.3 ± 8.43 a | 0.58 ± 0.026 a |
| βCAR-10 | 2.7 ± 0.09 ab | 65.8 ± 4.06 ab | 19.8 ± 1.42 ab | 230.4 ± 7.61 ab | 1.91 ± 0.023 ab |
| βCAR-20 | 3.1 ± 0.13 b | 69.2 ± 2.12 ab | 16.0 ± 1.07 b | 245.9 ± 11.8 ab | 2.31 ± 0.068 ab |
Data are represented as mean ± S.E. of 6 rats per group. a, b denotes significant difference from sham and I/R control groups, respectively, at p ≤ 0.05.