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Effect of MLN-4760 on exploratory behaviour and anxiety-like behaviour in OF (A–D) and EPM (E–H) test. Values represent the mean ± SEM (n = 11 per group). x p < 0.05 vs. basal values of the same group. Data were analyzed by repeated measures ANOVA (OF test) or Student’s t-test (EPM test). ANOVA analysis was followed with Bonferroni’s post-hoc test. Abbreviations: Cont, control group; MLN, MLN-4760-treated group.
