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. 2022 Dec 8;9:1051828. doi: 10.3389/fnut.2022.1051828

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Copyright © 2022 Kwon, Park, Lee, Park, Choo, Lee and Lee.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Comparison of sweating activity between subjects in CON and Coffee groups at axon reflex (AXR) (1) and AXR (2). (B) Comparison of estimated value on remove heat energy of whole body between CON and Coffee groups at AXR (1) and AXR (2). AXR (1) = 0–5 min and AXR (2) = 6–11 min. Values are means + SD. Statistical significance difference, *p < 0.05. CON, no coffee group (n = 40); Coffee, coffee intake group (n = 40); AXR, axon reflex mediated; AXR (1), AXR sweating during 5 min 10% acetylcholine (ACh) iontophoresis; AXR (2), AXR sweating during 5 min post-iontophoresis.