Table 1.
ARGs profile of 14 E. coli genomes carrying mcr-1.
| Class | Antibiotics | Number of mcr-1 + E. coli (%) | Gene Name (n) |
|---|---|---|---|
| Aminoglycoside | gentamicin | 8 (57) | aac(3)-IIa (2), aac(3)-IId (4), aac(3)-IVa (1), aac(3)-VIa (1) |
| hygromycin B | 1 (7) | aph(4)-Ia (1) | |
| kanamycin | 11 (79) | aph(3’)-Ia (5), aph(3’)-IIa (4), aph(6)-Id (6) | |
| streptomycin | 13 (93) | aadA2 (6), aadA5 (1), aadA15 (1), aadA17 (2), ant(3’’)-Ia (8), aph(3’’)-Ib (4) | |
| Beta-lactam | ampicillin | 10 (71) | blaTEM-1A (1), blaTEM-1B (8), blaTEM-141 (1) |
| ceftriaxone | 5 (36) | blaCTX-M-55 (5) | |
| Quinolone | ciprofloxacin | 10 (71) | qnrB19 (9), qnrD1 (1), qnrS2 (1) |
| Folate pathway antagonist | trimethoprim | 10 (71) | dfrA1 (3), dfrA8 (1), dfrA12 (6), dfrA14 (1), dfrA17 (1) |
| Fosfomycin | fosfomycin | 5 (36) | fosA3 (4), fosA6 (1) |
| Glycylcycline | tetracycline | 14 (100) | tet(A) (13), tet(B) (3), tet(D) (1), tet(M) (4) |
| lincomycin | 7 (50) | Inu(F) (7) | |
| Macrolide | erythromycin | 1 (7) | mph(A) (1) |
| Phenicol | chloramphenicol | 11 (79) | cmlA1 (6), floR (10) |
| Sulphonamide | sulfamethoxazole | 13 (93) | sul1 (3), sul2 (7), sul3 (9) |