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Multiple sequence alignment of H. sapiens COQ4, S. cerevisiae COQ4, and Nostoc sp. homolog Alr8543 (NCBI accession number: WP_010999537.1). Metal-liganding motif is boxed in cyan, and residues in Alr8543 (H120, D121, H124, and E136) that act to ligand the Mg2+ ions are marked with blue dots.
