Table 3.
Distribution by ST of QRDR and PMQR genes in isolates resistant to quinolones.
| Isolate | ST | PQMR | QRDR | gyrA | parC | ||
|---|---|---|---|---|---|---|---|
| 83 | 87 | 80 | 87 | ||||
| S-1226 | 307 | qnrB | 2 | Ile (ATC) * | Asp (GAC) | Ile (ATT) * | Glu (GAA) |
| CC4 | 307 | qnrB | 2 | Ile (ATC) * | Asp (GAC) | Ile (ATT) * | Glu (GAA) |
| H18-2354 | 307 | qnrB | 2 | Ile (ATC) * | Asp (GAC) | Ile (ATT) * | Glu (GAA) |
| O-3651 | 307 | qnrB | 2 | Ile (ATC) * | Asp (GAC) | Ile (ATT) * | Glu (GAA) |
| HR-0054 | 307 | qnrB | 2 | Ile (ATC) * | Asp (GAC) | Ile (ATT) * | Glu (GAA) |
| 164605 | 307 | qnrB | 2 | Ile (ATC) * | Asp (GAC) | Ile (ATT) * | Glu (GAA) |
| S-0734 | 152 | qnrB | 3 | Phe (TTC) * | Ala (GCC) * | Ile (ATC) * | Glu (GAA) |
| O-2723 | 405 | qnrB | 0 | Ser (TCC) | Asp (GAC) | Ser (AGC) | Glu (GAA) |
| CC5 | 2073 | qnrA | 0 | Ser (TCC) | Asp (GAC) | Ser (AGC) | Glu (GAA) |
Abbreviations: PMQR: plasmid mediated quinolone resistance; QRDR: quinolone resistance determining region; ST: sequence typing. * Substitutions: Ala: alanine; Asp: aspartic acid; Glu: glutamine; Ile: isoleucine; Phe: phenylalanine; Ser: serine.