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. 2022 Dec 14;11(12):2461. doi: 10.3390/antiox11122461

Figure 2.

Figure 2

SM reduces the infiltration of macrophages and inhibits the ROS-induced secretion of IL-1β in the kidneys of ApoE−/− 5/6 Nx mice. (A) Expression of F4/80 macrophages, (B) P-IKKα expression, and (C) IL-1β expression, as indicated by immunohistochemistry (IHC) staining; scale bar = 100 μm. Quantification of renal (D) MDA and (E) GPx levels in the kidneys of 5/6 Nx mice. Data are expressed as the mean ± SEM (n = 6). ** p < 0.01, *** p < 0.001 vs. sham group. # p < 0.05, ## p < 0.01, ### p < 0.001 vs. 5/6 Nx group.