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. 2022 Dec 19;11(12):2499. doi: 10.3390/antiox11122499

Table 3.

Echocardiographic assessment and parameters evaluated in db/db mouse model. Data are expressed as mean ± SEM of each group (db/m, n = 8; db/db, n = 8; db/db + H, n = 8). * p < 0.05 vs. db/m analyzed separately by Mann–Whitney U test. Abbreviations: IVS, interventricular septum; LVID, LV internal dimension; PW, LV posterior wall. All thicknesses in diastole (d) and systole (s). BW, body weight correction; EF, LV ejection fraction; FS, LV fractional shortening; PWT, LV posterior wall thickening.

Variables db/m db/db db/db + H
IVSd (μm) 102.4 ±4.3 115.4 ± 15.2 109.6 ± 15.1
LVIDd (μm) 379.5 ± 4.8 336.2 ± 46.6 336.3 ± 37.1
PWd (μm) 99.0 ± 2.4 106.2 ± 12.9 94.2 ± 11.8
IVSs (μm) 144.8 ± 2.7 171.9 ±18.9 165.8 ± 18.0
LVIDs (μm) 260.0 ± 4.5 222.4 ± 36.7 219.2 ± 25.3
PWs (μm) 138.6 ±2.4 137.1 ± 13.9 120.4 ± 16.9
LV mass (μg) 148.6 ± 4.7 146.4 ± 19.5 125.3 ± 16.6
LV mass/BW (μg/g) 5.0 ± 0.2 2.6 ± 0.4 * 2.4 ± 0.3 *
EF (%) 67.1 ± 2.4 71.2 ± 9.9 72.1 ± 10.2
FS (%) 31.3 ± 1.6 34.2 ± 5.0 35.4 ± 5.4
PWT (%) 40.5 ± 5.1 28.8 ± 7.4 29.2 ± 8.3