Skip to main content
. 2022 Dec 9;11(12):2438. doi: 10.3390/antiox11122438

Figure 2.

Figure 2

(A,B) Representative electron micrographs from control (CO) (A) and TS (B) GC bodies. Note typical small round or oval mitochondria in the control GC and the presence of larger and polymorphic mitochondria in the TS GC (asterisks). N: nucleus. (C,D) Elongated and polymorphic mitochondria in cell bodies of TS GCs (asterisks). (E,F) Detail of structural alterations in TS GC mitochondria with swelling of the matrix (MS) (E) and focal disruption of cristae (MD) (F). (G,H) RT-qPCR determination of Pink1 (G) and Prkn1 (H) gene expression in hippocampal RNA extracts from control (CO) and TS mice. Pink1 is upregulated, and a moderate but non-significant increase in Prkn1 was detected in TS hippocampi. Data in (G,H) are presented as means ± SEMs of three independent experiments. #: p < 0.05.