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Polymyxin B dosing and PK/PD data.
| Dose | IV/IVT: 50,000 units once daily (in combination with systemic therapy) |
| Indication/targeted organisms | CSF Shunt-related meningitis (MDR Pseudomonas aeruginosa, Acinetobacter baumannii, Klebsiella pneumoniae) |
| PD/PD Data | CSF/serum concentrations: No data available Percent protein binding: 58% Serum half-life: 9–11.5 h Cmax: 2–14 mcg/mL |
