Figure 7.

Mediating effect among WMH volume, ALPS-index, and episodic memory score in the CSVD-MCI group. Solid lines indicate direct effects (c’); dashed lines indicate indirect effects (a ∙ b). Associations are given as non-standardized regression coefficients (non-standardized ß). Gender, age, hypertension, and years of education were used as covariates. Abbreviations: WMH, white matter hyperintensities; ALPS-index, the index of Diffusion Tensor Image Analysis along the Perivascular Space; CSVD, cerebral small vessel disease; MCI, mild cognitive impairment. *: p < 0.05.