Table 1.

Summary of advantages, disadvantages, and prerequisites of the revascularization approach.

Advantages [64,65,66,67]	Disadvantages [64,65,66,67]	Prerequisites [30,68,69,70]
Technically simple. Technique can be used without expensive biotechnology. Chances of immune rejection and pathogen transmission are negligible. Microleakage negligible Concerns of restoration retention are negligible. In immature teeth, the walls of the rots are reinforced. New developed tissues can easily access the root canal system. Preserve vital tissue as minimum instrumentation Rapid capacity to heal the tissue in young patients More regenerative potential in young patients	It is still not known from which source the tissue can be regenerated. Blood-clot formation is not the factor on which tissue engineering relies. Treatment outcome will vary with changes in the concentration and composition of cells.	Necrotic pulp secondary to trauma, open apices, and permanent dentition. Tooth must have thin walls. Effective coronal seal Matrix for the growth of new tissues Canal should not be instrumented. Blood-clot formation Sodium hypochlorite as an irrigant Non-vital traumatized tooth If treatment procedures, such as apexogenesis, apexification, partial pulpotomy, or root canal obturation, are not suitable, then only this treatment approach will be used.