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. 2022 Nov 28;10(12):3056. doi: 10.3390/biomedicines10123056

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Serological and histological inflammatory read-outs. (A) Circulating levels of leukocytes and (B) neutrophils during the 7-day follow-up period. (C) Circulating levels of C-reactive protein (CRP) during the 7-day follow-up. (D) Myocardial interleukin (IL)-1β levels, measured in infarct (I) and border zone (BZ) regions of the pig heart. Data are presented as mean ± SEM (p-values following mixed models testing). N.B. The first three timepoints of the analysis are baseline, 4 h after reperfusion, and 24 h.