Table 1.

Infarct size and cardiac function 7 days after MI and treatment. AAR, area at risk; LV, left ventricle; IS, infarct size. EDV, end-diastolic volume; ESV, end-systolic volume; EF, ejection fraction.

Group	AAR/LV ± SD	IS/AAR ± SD	IS/LV ± SD	EDV (mL)	ESV (mL)	EF%
Placebo (n = 6)	26.8 ± 6.1%	73.1 ± 3.0%	19.6 ± 4.5%	140.2 ± 21.2	80.5 ± 20.2	45.1 ± 8.7%
1 mg/kg IZD334 (n = 6)	23.5 ± 3.2%	75.5 ± 7.3%	17.7 ± 6.3%	149.6 ± 26.2	71.5 ± 18.7	49.9 ± 6.1%
3 mg/kg IZD334 (n = 7)	26.0 ± 1.9%	80.3 ± 3.9%	20.5 ± 2.2%	151.4 ± 7.6	86.8 ± 8.2	42.7 ± 3.8%
10 mg/kg IZD334 (n = 7)	26.38 ± 6.6	78.2 ± 8.0%	19.3 ± 2.9%	144.0 ± 22.0	80.0 ± 18.9	44.9 ± 6.4%