Table A1.
Histological analysis and myocardial IL-1β measurement.
| IZD334 | ||
|---|---|---|
| Route | PO | IV |
| T1/2 (h) | - | 3.9 |
| MRT0-inf (h) | - | 5.3 |
| Cl (mL/min/kg) | - | 1.8 |
| Vdss (L/kg) | - | 0.58 |
| Cmax (ng/mL) | 12,116 | - |
| AUC0-inf (ng.h/mL) | 86,337 | 27,786 |
| F% | 93 | |
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