Table 1.
Eligible studies’ baseline characteristics.
| Study | Age and Prior Events | Clinical Presentation (Included and Pooled) | Procedural Data and Medication | Attrition, Cross-Overs | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Stent | TiNOS | DES | TiNOS N incl, % pooled |
DES N incl, % pooled |
TiNOS | DES | ||||
| TITAX-AMI DES = PES [36,37] |
Patients n age prior MI prior PCI prior CABG |
214 64 ± 11 15% 10% 7% |
211 64 ± 11 9% 5% 6% |
NSTEMI STEMI UA |
131, 61% 83, 39% 0, 0% |
114, 54% 97, 46% 0, 0% |
Stents/culprit lesion n TSL (mm) post-dilation procedural success DAPT 12 m |
1.1 ± 0.3 18.5 ± 6.4 42% 99.5% 31% |
1.1 ± 0.4 19.2 ± 7.2 35% 98.1% 65% |
LFU 1 y TiNOS: 0 DES: 0 5 y TiNOS 3 DES: 7 |
| TIDE DES = ZES [38,39] |
Patients n age prior MI prior PCI prior CABG |
152 65.9 ± 9.0 27.6% 25.7% 7.9% |
150 63.4 ± 10.5 28.7% 21.3% 25.3% 2.7% |
Stable angina NSTEMI UA |
57.9% 32.9% 9.2% |
47.3% 42.0% 10.7% |
Stents/culprit lesion n TSL (mm) device success DAPT 12 m |
1.28 ± 0.55 19.3 ± 11.1 93.0% |
1.17 ± 0.45 19.6 ± 10.0 94.6% |
LFU 1 y TiNOS: 0 DES: 2 5 y: N.R. |
| TITANIC-XV DES = EES [40] |
Patients n age prior MI prior PCI prior CABG |
83 66.5 ± 8.8 10.8% 8.4% 2.4% |
90 64.5 ± 10.1 15.6% 11.1% 2.2% |
NSTEMI other CAD Diabetics: all |
69.9% 30.1% |
60.0% 40.0% |
Stents/culprit lesion n TSL (mm) stent failure DAPT 12 m |
1.1 ± 0.3 18.72 ± 8.20 NR. |
1.1 ± 0.3 21.63 ± 9.65 NR. |
NR. |
| BASE-ACS DES = EES [41,42] |
Patients n age prior MI prior PCI prior CABG |
417 63 ± 12 13.4% 9.6% 4.8% |
410 63 ± 12 9.8% 10.5% 4.1% |
NSTEMI STEMI UA |
206, 49.4% 162, 38.8% 49, 11.8% |
187, 45.6% 159, 38.8% 64, 15.6% |
Stents/culprit lesion n TSL (mm) post-dilation stent failure DAPT: Aspirin: N.R. Clopidogrel: N.R. |
1.15 ± 0.38 20.8 ± 9.4 42.2% 0.0% |
1.14 ± 0.36 20.6 ± 8.2 43.9% 1.0% |
LFU 1 y TiNOS: 3 DES: 3 5 y TiNOS 29 DES: 28 |
| TIDES-ACS DES = EES [43,44] |
Patients n age prior MI prior PCI prior CABG |
989 62.7 ± 10.7.6% 7.0% 0.6% |
502 62.6 ± 10.5 9.0% 6.6% 1.2% |
NSTEMI STEMI |
46.3% 44.9% |
45.0% 47.6% |
Stents/culprit lesion n TSL (mm) post-dilation stent failure DAPT 12 m |
1.13 ± 0.38 20.5 ± 7.8 33.0% 0.3% 80.3% |
1.14 ± 0.37 20.6 ± 7.2 38.0% 1.0% 86.0% |
LFU 1 y TiNOS: 7 DES: 4 |
UA = unstable angina pectoris; Drugs: EES = everolimus elution; ZES = zotarolimus elution; PES = paclitaxel elution; 12 m = 12 months; 1 y = 1 year.