Table 4.

Available evidence for age groups.

	Children (<14 years)		Adolescents (≥14 years)
	Quality	Summary of Findings	Quality	Summary of Findings
Olanzapine	2 case reports/series	−weight gain (1/2); weight restored (1/2) −no ADR reported −reduced rituals and compulsions (2/2); improvement in anxiety and agitation (1/2); better in sleeping (1/2)	5 case reports	−reduction in abnormal eating habits (2/5); anxiety and agitation (1/5); irritability, compulsive thoughts about body weight and physical activity; no data collected (1/5); no improvement (1/5) −weight gain (4/5); no improvement (1/5) −no ADR reported (3/5); mild sedation (1/5); NMS (1/5)
Risperidone	3 case reports	−weight gain −no ADR reported (2/3); refusal oral formulation (1/3) −decrease in agitation (2/3); improvement in paranoid and distorted thoughts (2/3); cheerful and energetic (1/3)	1 case report	−weight gain −improvement in rigidity during mealtime −no ADR reported
Aripiprazole	/		/
Quetiapine	/		1 case report	−weight gain −improved in anxiety and mood stability −no ADR reported
Clotiapine	/		1 retrospective chart review	−weight: na −decrease delusional thinking and restored proper hygiene habits −fatigue
Chlorpromazine	2 case reports	−weight restored (2/2) −scarce data on psychopathology −one grand mal seizure (association unclear)	1 case report	−weight restored −increased caloric intake −no ADR reported
Haloperidol	/		/	−
Pimozide	/		1 case report	−weight gain −reduction in hyperactivity and obsessive thoughts about weight −no ADR reported
Sulpiride	/		1 case report	−weight gain −decrease in distorted self-image and thoughts around food −no ADR reported