Table 1.
mRNA analysis: Factors that were over-represented in the HUNK altered group assessed using GO Biological Processes, KEGG, and Reactome databases that were consolidated by the STRING analysis.
| Pathway (Higher in HUNK Altered) | Observed Gene Count | Background Gene Count | False Discovery Rate |
|---|---|---|---|
| GO Biological Processes | |||
| Immune system process | 90 | 2481 | 5.53 × 10−20 |
| Immune response | 63 | 1588 | 1.98 × 10−14 |
| KEGG | |||
| T cell receptor signaling pathway | 12 | 101 | 1.16 × 10−6 |
| Chemokine signaling pathway | 15 | 186 | 1.32 × 10−6 |
| Cytokine–cytokine receptor interaction | 16 | 282 | 2.50 × 10−5 |
| Reactome | |||
| TCR signaling | 12 | 112 | 7.21 × 10−6 |
| Chemokine receptors bind chemokines | 8 | 68 | 0.00021 |
| Cytokine Signaling in Immune system | 23 | 681 | 0.0012 |
| Pathway (lower in HUNK altered) | |||
| GO Biological Processes | |||
| Homophilic cell adhesion via plasma membrane adhesion molecules | 15 | 164 | 5.44 × 10−10 |