TABLE 2.

Comparison and homology of sub-amino-terminal sequences within ML family isolates

Peptidea	Sequenceb	% Similarity	Location in M protein
ML2 family
203246–59	KVEEEHKKDHEKLE		B repeat
BSA10(54–67)	--------------	100
NS14(45–58)	--K------K----	93
ML60 family
203440–59	DDKEKDPQYRALMGENQDLR		Nonrepetitive region
2080(56–75)	-NIR---------------M	85
Y530S(41–60)	-NTR---------------M	85
TIN family
Y504S45–64	EETKNKELDKKNKELDSRVT		Follows A repeat
90/85(39–58)	LLD-QE--E-E-EK---Q-A	45
88/544(41–60)	LTE--E-------K---Q-D	65
M52/53/80 family
88/2533–53	SENEELQAGLQEKERELEDL		A1 repeat
2072(39–58)	------K-D--K--Q--KN-	70
NS27(37–56)	--K---ETE-----Q--KN-	65
NS5(36–55)	----G-K-------Q--KN-	75
87/156(35–54)	------K-D--K--Q--KN-	70
2317(34–53)	-A----ETT--K--Q--KG-	60
M41(35–54)	RR-N--EKII--------G-	60
M12/M55 family
204050–69	LKMLNRDLEQAYNELSGEAH		B1 repeat
2075(58–77)	--E--DEF---------DGV	85
2033(56–75)	--G--DWA-RLLQ--N--DV	45
2040239–258	AALGHQHAHNEYQAKLAEKD
2033(268–287)	--------------------	100

^aSubscripts in parentheses are the amino acid positions of each sequence corresponding to the peptide. Adapted from Relf (27). 

^bIdentical residues are shown as dashes.