Figure 5.

Effects of inhibition of cardiac mtp and exercise training on mRNA expression in Drosophila. All samples (N = 50 per group) were virgin flies of 10 days. (A) The cardiac mRNA expression levels of Drosophila under different treatments, on the one hand, HFD decreased the mRNA expression levels of cardiac mtp in the w¹¹¹⁸ and Hand > w¹¹¹⁸ groups; on the other hand, HFD did not significantly affect the mRNA expression levels of cardiac mtp in Hand > mtp^RNAi Drosophila. In contrast, exercise training in Drosophila with HFD upregulated the mRNA expression levels of cardiac mtp in all Drosophila of HFD. (B) M-mode ECG of Drosophila in the Hand > mtp^RNAi group, the blue line is the systolic interval, and the red line is the diastolic interval. In (A), one-way ANOVA was used to identify differences between strains of Drosophila NFD, HFD and HFD +E. LSD was used for post hoc testing.