Table 1.
Clinicopathological characteristics of the in silico cohort (n = 327).
| Characteristic | Count | % | |
|---|---|---|---|
| Age at diagnosis | 19–90 years; median 61 years | − | |
| Sex | Female | 101 | 32.0% |
| Male | 225 | 68.0% | |
| Positive history of nicotine abuse | No | 78 | 23.9% |
| Yes | 247 | 74.9% | |
| N/A | 2 | 1.2% | |
| Positive history of alcohol abuse | No | 107 | 32.7% |
| Yes | 219 | 67.0% | |
| N/A | 1 | 0.3% | |
| Tumor site | Tongue | 129 | 39.4% |
| Oral cavity | 67 | 20.5% | |
| Floor of mouth | 59 | 18.1% | |
| Base of tongue | 23 | 7.0% | |
| Buccal mucosa | 22 | 6.7% | |
| Alveolar ridge | 17 | 5.2% | |
| Hard palate | 7 | 2.1% | |
| Lip | 3 | 1.0% | |
| Tumor size | T1 | 33 | 10.1% |
| T2 | 101 | 30.9% | |
| T3 | 68 | 20.8% | |
| T4 | 11 | 3.4% | |
| T4a | 95 | 29.0% | |
| T4b | 4 | 1.2% | |
| Tx | 15 | 4.6% | |
| Cervical node stage | N0 | 168 | 51.5% |
| N1 | 60 | 18.4% | |
| N2a | 45 | 13.9% | |
| N2b | 25 | 7.7% | |
| N2c | 11 | 3.5% | |
| N3 | 7 | 2.1% | |
| Nx | 4 | 1.2% | |
| N/A | 7 | 2.1% | |
| Tumor grade | G1 | 48 | 14.5% |
| G2 | 201 | 61.1% | |
| G3 | 65 | 19.6% | |
| G4 | 4 | 2.1% | |
| Gx | 6 | 1.7% | |
| N/A | 3 | 1.0% |