Table 2.
Patients’ clinicopathological characteristics according to TIGIT expression of CD3+ cells (median cutoff; n = 76).
| χ2 TIGIT Median Cut-Off | ||||||
|---|---|---|---|---|---|---|
| ≤Median | >Median | p | ||||
| Count | % | Count | % | |||
| Age at diagnosis | <70.0 | 31 | 66.0% | 24 | 82.8% | 0.112 |
| ≥70.0 | 16 | 34.0% | 5 | 17.2% | ||
| Sex | Female | 15 | 31.9% | 12 | 41.4% | 0.402 |
| Male | 32 | 68.1% | 17 | 58.6% | ||
| Positive history of nicotine abuse |
No | 12 | 25.5% | 5 | 17.2% | 0.399 |
| Yes | 35 | 74.5% | 24 | 82.8% | ||
| Positive history of alcohol abuse |
No | 10 | 21.3% | 11 | 37.9% | 0.115 |
| Yes | 37 | 78.7% | 18 | 62.1% | ||
| Tumor size | T1 | 6 | 12.8% | 11 | 37.9% | 0.047 |
| T2 | 22 | 46.8% | 8 | 27.6% | ||
| T3 | 5 | 10.6% | 1 | 3.4% | ||
| T4a | 14 | 29.8% | 9 | 31.0% | ||
| T4b | 0 | 0.0% | 0 | 0.0% | ||
| Cervical node status | N0 | 23 | 48.9% | 16 | 55.2% | 0.795 |
| N1 | 8 | 17.0% | 4 | 14.0% | ||
| N2a | 2 | 4.3% | 0 | 0.0% | ||
| N2b | 9 | 19.1% | 5 | 17.2% | ||
| N2c | 5 | 10.6% | 4 | 14.0% | ||
| N3a | 0 | 0.0% | 0 | 0.0% | ||
| N3b | 0 | 0.0% | 0 | 0.0% | ||
| Tumor grade | G1 | 0 | 0.0% | 2 | 6.9% | 0.047 |
| G2 | 39 | 83.0% | 26 | 89.7% | ||
| G3 | 8 | 17.0% | 1 | 3.4% | ||
| G4 | 0 | 0.0% | 0 | 0.0% | ||
| Lymph vessel invasion | L0 | 35 | 74.5% | 24 | 82.8% | 0.399 |
| L1 | 12 | 25.5% | 5 | 17.2% | ||
| Vessel invasion | V0 | 44 | 93.6% | 27 | 93.1% | 0.930 |
| V1 | 3 | 6.4% | 2 | 6.9% | ||
| Perineural invasion | Pn0 | 46 | 97.9% | 27 | 93.1% | 0.300 |
| Pn1 | 1 | 2.1% | 2 | 6.9% | ||
| Adjuvant therapy | No | 21 | 44.7% | 12 | 41.4% | 0.931 |
| Radiotherapy | 19 | 40.4% | 13 | 44.8% | ||
| Radiochemotherapy | 7 | 14.9% | 4 | 13.8% | ||
| total | 47 | 100.0% | 29 | 100.0% | ||