Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Dec 8;12(12):1837. doi: 10.3390/biom12121837

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Regulation of the cytoskeleton by cyclic stretch. Cell stiffness of (A) HUVECs and (B) rapamycin-treated HUVECs as determined through AFM. * indicates p < 0.05 between respective groups. (C) Heatmap demonstrating the expression of cytoskeletal component genes grouped into their respective classifications in response to 10% and 20% stretch. (D) Heatmap demonstrating the expression of cytoskeletal mTOR-target genes grouped into their respective classifications in response to 10% and 20% stretch. For both (C,D), expression was normalized to the static (no stretch) control. Cytoskeletal genes were identified through the Molecular Signatures Database.

Regulation of the cytoskeleton by cyclic stretch. Cell stiffness of (A) HUVECs and (B) rapamycin-treated HUVECs as determined through AFM. * indicates p < 0.05 between respective groups. (C) Heatmap demonstrating the expression of cytoskeletal component genes grouped into their respective classifications in response to 10% and 20% stretch. (D) Heatmap demonstrating the expression of cytoskeletal mTOR-target genes grouped into their respective classifications in response to 10% and 20% stretch. For both (C,D), expression was normalized to the static (no stretch) control. Cytoskeletal genes were identified through the Molecular Signatures Database.